The Ras pathway patterns the poles of the Drosophila embryo by downregulating the levels and activity of a DNA-binding transcriptional repressor Capicua (Cic).We demonstrate that the spatiotemporal pattern of Cic during this signaling event can be harnessed for functional studies of mutations in the Ras pathway in human diseases.Our approach relies

Today, the rapid growth of cities and massive migrations towards them has resulted in wide cultural diversity in urban environments, and this issue has made the local governments who are responsible for the management of cities face a serious problem, that is why the opi the color that keeps on giving management a city in big cities will no longer

The aim of this study was to investigate neuropsychological features of adolescents with the Internet-addictive behavior.The sample comprised 756 adolescents with 316 females (40,2%) and 340 bilstein shocks jeep xj males (59,8%).The mean age was 15,5 years.The main experimental group (42 adolescents) included only those respondents who had high lev

Idiopathic pulmonary arterial hypertension (IPAH) is a life-threatening cardiopulmonary disease lacking specific diagnostic markers and targeted therapy, and its mechanism of development remains to be elucidated.The present study aimed to explore novel diagnostic biomarkers and click here therapeutic targets in IPAH by integrated bioinformatics ana